| Jornada 1 | 19/08/2012 | RAYO VALLEC. | 1 | GRANADA | 0 |
| Jornada 2 | 26/08/2012 | BETIS | 1 | RAYO VALLEC. | 2 |
| Jornada 3 | 02/09/2012 | RAYO VALLEC. | 0 | SEVILLA | 0 |
| Jornada 4 | 16/09/2012 | ATLETICO MADRID | 4 | RAYO VALLEC. | 3 |
| Jornada 5 | 23/09/2012 | RAYO VALLEC. | 0 | REAL MADRID | 2 |
| Jornada 6 | 30/09/2012 | VALLADOLID | 6 | RAYO VALLEC. | 1 |
| Jornada 7 | 07/10/2012 | RAYO VALLEC. | 2 | DEPORTIVO | 1 |
| Jornada 8 | 21/10/2012 | ESPANYOL | 3 | RAYO VALLEC. | 2 |
| Jornada 9 | 28/10/2012 | RAYO VALLEC. | 0 | FC BARCELONA | 5 |
| Jornada 10 | 04/11/2012 | MALAGA | 1 | RAYO VALLEC. | 2 |
| Jornada 11 | 11/11/2012 | RAYO VALLEC. | 3 | CELTA | 2 |
| Jornada 12 | 18/11/2012 | REAL SOCIEDAD | 4 | RAYO VALLEC. | 0 |
| Jornada 13 | 25/11/2012 | RAYO VALLEC. | 2 | MALLORCA | 0 |
| Jornada 14 | 02/12/2012 | OSASUNA | 1 | RAYO VALLEC. | 0 |
| Jornada 15 | 09/12/2012 | RAYO VALLEC. | 0 | ZARAGOZA | 2 |
| Jornada 16 | 16/12/2012 | VALENCIA | 0 | RAYO VALLEC. | 1 |
| Jornada 17 | 22/12/2012 | RAYO VALLEC. | 3 | LEVANTE | 0 |
| Jornada 18 | 06/01/2013 | RAYO VALLEC. | 3 | GETAFE | 1 |
| Jornada 19 | 13/01/2013 | ATHLETIC BILBAO | 1 | RAYO VALLEC. | 2 |
| Jornada 20 | 20/01/2013 | GRANADA | 2 | RAYO VALLEC. | 0 |
| Jornada 21 | 27/01/2013 | RAYO VALLEC. | 3 | BETIS | 0 |
| Jornada 22 | 03/02/2013 | SEVILLA | 2 | RAYO VALLEC. | 1 |
| Jornada 23 | 10/02/2013 | RAYO VALLEC. | 2 | ATLETICO MADRID | 1 |
| Jornada 24 | 17/02/2013 | REAL MADRID | 2 | RAYO VALLEC. | 0 |
| Jornada 25 | 24/02/2013 | RAYO VALLEC. | 1 | VALLADOLID | 2 |
| Jornada 26 | 03/03/2013 | DEPORTIVO | 0 | RAYO VALLEC. | 0 |
| Jornada 27 | 10/03/2013 | RAYO VALLEC. | 2 | ESPANYOL | 0 |
| Jornada 28 | 17/03/2013 | FC BARCELONA | 3 | RAYO VALLEC. | 1 |
| Jornada 29 | 31/03/2013 | RAYO VALLEC. | 1 | MALAGA | 3 |
| Jornada 30 | 07/04/2013 | CELTA | 0 | RAYO VALLEC. | 2 |
| Jornada 31 | 14/04/2013 | RAYO VALLEC. | 0 | REAL SOCIEDAD | 2 |
| Jornada 32 | 21/04/2013 | MALLORCA | 1 | RAYO VALLEC. | 1 |
| Jornada 33 | 28/04/2013 | RAYO VALLEC. | 2 | OSASUNA | 2 |
| Jornada 34 | 05/05/2013 | ZARAGOZA | 3 | RAYO VALLEC. | 0 |
| Jornada 35 | 12/05/2013 | RAYO VALLEC. | 0 | VALENCIA | 4 |
| Jornada 36 | 19/05/2013 | LEVANTE | 2 | RAYO VALLEC. | 3 |
| Jornada 37 | 29/05/2013 | GETAFE | 1 | RAYO VALLEC. | 2 |
| Jornada 38 | 01/06/2013 | RAYO VALLEC. | 2 | ATHLETIC BILBAO | 2 |